Cell population heterogeneity driven by stochastic partition and growth optimality

https://arxiv.org/pdf/1805.07768.pdf

Jorge Fernandez-de-Cossio-Diaz, Roberto Mulet, Alexei Vazquez

• The authors suggest that a cellular quantity which i) has an optimal value for growth rate; ii) is stochastically partitioned at cell division; may display a bimodal distribution in the population. 
• Whether the distribution is unimodal or bimodal depends on the sharpness of (i) and the extent of noise in (ii). The authors suggest mitochondria as a potential cellular component for which their theory is applicable.