Wei Qian, Namrata Kumar, Vera Roginskaya, Elise Fouquerel, Patricia L. Opresko, Sruti Shiva, Simon C. Watkins, Dmytro Kolodieznyi, Marcel P. Bruchez, and Bennett Van Houten
- The authors develop a chemoptogenetic technology to specifically induce mitochondrial reactive oxygen species with precise spatio-temporal control by using light stimulation.
- The authors show that induction of mitochondrial reactive oxygen species can result in increased hydrogen peroxide levels inside the nucleus, resulting in telomere loss.